Melasma is skin disorder and many chemical peels are now available for the treatment. These chemical peels causes in depth injury at a specific skin that stimulates the new skin growth and improves the skin appearance and texture. The comparative study was done between three chemical peels such as 70% glycolic acid, 35% TCA, and 1% tretinoin to test for efficacy and side effects. Results showed 65%, 59%, 50% reduction in MSI score in glycolic acid, TCA and tretinoin respectively. Considerable reduction was observed in all three chemical peels with different side effects.