The skin is an essential organ with diverse functions. A deep molecular understanding to the biology of skin can offer explanations to many dermatological diseases. Furthermore, the skin perhaps serves the best model for cell biology research ranging from adult stem cell research to general questions in cancer and in development.
The skin offers a multiple advantages to be used as a model system that other tissues do not possess. Advantages of skin as a study model include: simple visualization, large size, less complex cell culture systems, and efficient physiological readouts. Here, I would address two recent findings in the field of stem cell biology using the skin as model system, and this might bring forward revolutionary outcomes in the biomedical field.