Dermatology

Seborrheic Dermatitis

Posted on

dermatitis journal articlesIt is also known as sebopsoriasis, seborrhei eczema, dandruff and pityriasis capitis. It is a chronic, relapsing and usually mild dermatitis while in infants seborrheic dermatitis is usually known as cradle cap. Seborrheic dermatitis is considered to be an inflammatory where skin disorder affecting the scalp, face and torso. That red, itchy rash on your scalp that has flaky scales could be seborrheic dermatitis, or seborrhea. It’s a common skin disease that looks similar to psoriasis, eczema, or an allergic reaction. And it can appear on your body as well as your scalp.

Vitiligo: Skin Malignancies and Tumor Suppressive Marker P53

Posted on Updated on

Vitiligo is common autoimmune pigmentary disorders where there are no cutaneous cancers have been reported among affected patients. To estimate the frequency P53 marker and its role in protection against skin cancers in patients with vitiligo. Patients and Methods: This study took place in the Department of Dermatology, Baghdad Hospital during the period from May 2009-September 2010.

journal of pigmentary disorders impact factor

It is composed of two parts: Part I was case descriptive study performed to record any association of skin malignancies in 300 vitiligo patients, 155 females and 145 males, while Part II was case observational, controlled, histochemical, investigative study to estimate the frequency of P53 in vitiliginous skin and adjacent normal skin in comparison with control group. Skin biopsies were taken from 25 patients, one from the centre of vitiliginous patch and the other about 0.5 cm adjacent to the patch (normal skin).

Local Natural Medicine Wisdom and Medical Cosmetology

Posted on Updated on

journal cosmetology dermatologyBeautiful has been the topic of interest for a long time. Everyone like a beauty appearance and the cosmetology is the specific science for promotion of beauty. The medical cosmetology is widely practice at present. Many new advance cosmetic materials and techniques are available. Most of them are artificial and synthesized. Based on the concept of green technology and think earth at present, returning to the nature is the new concept. Of several fields of medicine in the present day, natural medicine is the specific medicine with the closest relationship to nature. It is interesting that the use of natural medicine in medical cosmetology should be promoted. In fact, there are several local wisdoms regarding the beauty promotion and this should be further studied and researched in medical cosmetology. Several herbal medicine systems have been reintroduced for a few years. As the local wisdom pass a long period of time, the safety and efficacy might be expected.

Download PDF

Heat Shock Proteins: Heating up skin cancer biology

Posted on Updated on

Heat shock proteins (HSPs) are molecular chaperones with significant role in various physiological processes and pathological conditions including cancer. Certain cytotoxic insults or heat stress causes activation of the HSPs, which prevent cells from undergoing apoptosis and maintenance of cellular function. However, activation of HSPs also has detrimental effects particularly if the cells evading apoptosis possess oncogenic mutations.

dermatitis journal articles

Over that last few decades there has been a steady rise in incidence of skin cancer globally and recent scientific and epidemiological evidence hypothesize that heat stress could also be a risk factor of skin carcinogenesis. More recently, HSP based vaccines have shown promise in treatment of early stage melanoma. Therefore, the aim of this article is to summarize the main concepts related to the expression and function of HSPs, from analysis of HSPs role in skin cancer and present final considerations related to HSP targeted therapy in this area.

Treatment of Posttraumatic Scar with Ablative Fractional Erbium: YAG Laser

Posted on Updated on

orofacial surgery impact factorScars following injuries are common and an important cause of concern to patients. They can be treated with various modalities including lasers. Recently, fractional lasers have emerged as an effective, safe modality in tackling this challenge. There are limited publications on the efficacy and safety of treatment of post trauma scars with fractional ablative laser. Here we are presenting a case of posttraumatic scar treated with fractional ablative erbium yag laser which showed significant improvement in colour, texture and overall appearance of the scar.

Download PDF

Erythrokeratoderma En cocardes with R32W Mutation in GJB3

Posted on Updated on

clinical dermatology research journalThe term erythrokeratodermia is applied to a group of inherited disorders of keratinisation characterized by well demarcated erythematous lesions and hyperkeratotic plaques. Erythrokeratoderma en cocardes is an atypical variant characterised by the presence of transient hyperkeratotic and erythematous plaques. The pathogenetic mechanisms of most of the erythrokeratodermia are related to mutations in the connexin gene family, but until now, there is no information concerning the genetic alterations that are responsible for the appearance of the erythrokeratoderma en cocardes. We report the case of a 31-year-old woman with a 5-year history of fixed erythematous plaques with scaly rims on the arms, trunk, axillae and limb flexures that disappeared spontaneously and recurred every summer.

Download PDF

Genetic Influences on Pharmacological Interventions in Psoriasis

Posted on Updated on

Psoriasis is a common chronic inflammatory disease that affects 2% of the population. Therapeutic intervention for psoriasis mainly targets inflammatory cascade through the use of topical agents, phototherapy, systemic agents and the newer biologic agents.

experimental dermatology journal

The efficacy of many treatments used in psoriasis varies from patient to patient, and some of this variance in response can presumably be attributed to genetic differences. While current research findings are still limited, the clinical utilization of pharmacogenetics allows for tailored treatment plans that have the potential for better response amongst patients as well as conserving expenditures and health care resources. In this review, we hope to focus and summarize the conclusions and findings of studies done on the topic of pharmacogenetics in the treatment of psoriasis.

Download PDF