Current Options and Future Directions for Managing Osteoporosis: An update

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Osteoporosis is considered as the most common metabolic bone disorder and characterized by low bone mass and skeletal fragility. Osteoporosis engages approximately about 200 millions of individuals, world widely. For instance, about 10 millions of Americans are affected and another 34 million are at risk of osteopenia . Osteoporosis has been known as a silent disease. The affected patients do not often understand about the nature of their disease until it significantly develops so that the patients are often presented with osteoporosis related fractures. Postmenopausal women are the most commonly affected population in the world and the fracture rates in postmenopausal Asian, American and African women have been reported to be 41, 54 and 91%, respectively.

Managing Osteoporosis

During the postmenopausal period, the risk of fractures increases due to the accelerated bone loss because estrogen declines with age. Moreover, men are also affected by osteoporosis with the incidence of 20%. Annually, $19 billion are accounted for osteoporotic fractures in health care expenditures which expected to rise to $25.3 billion in the future 10 years. Each year, nearly 300,000 hip fractures, 547,000 vertebral fractures and almost 1,054,000 other fractures occur due to osteoporosis. Osteoporosis imposes more than 432,000 hospital admissions, 2.5 million medical office visits, and 180,000 nursing home admissions to the healthcare systems, annually. Despite of several attempts, osteoporosis is still a considerable challenge for the governments.

Physical Properties of Calcium Phosphate-Alumina Bio ceramics as Dental Implants

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In order to perform new dental implant, we carried out investigations on α-alumina and calcium phosphate based composites. α-Alumina nano-powder were synthesized using reverse micelle method while calcium phosphate nano-powders with different molar ratio starting from 1.8 to 1.1 were synthesized by precipitation method, using calcium nitrate (Ca(NO3)2.4H2O) and ammonium hydrogen orthophosphate (NH4H2PO4) as precursor materials as source for calcium (Ca²+) and phosphate ((PO4)3-) ions respectively. Samples of respectively 5, 10 and 20% weight of Calcium phosphate powder were mixed with alumina, consolidated and sintered at 1400°C for 4 hours. The synthesized composites, in form of pellets were characterized for bulk density, apparent porosity, hardness and flexural strength properties.

Calcium Phosphate-Alumina Bio ceramics

Bioceramic materials particularly calcium phosphate based materials are used mainly as bone substitute or scaffolds due to their good biocompatibility, and their compositional similarity with the inorganic components of human bone. Many of these bioceramic materials also possess excellent chemical resistance, compressive strength and wear resistance. However, there are some bioceramic materials which are inert in their bioactive response.

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Journal of Psoriasis

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Psoriasis is a chronic skin disease.in this condition the cells are built on the surface of the skin. The extra skin cells form silvery scales and itchy which are often painful. The treatment for psoriasis can be carried out in a better way if we can stop the skin cells from growing so quickly. The top open access journals are peer reviewed scholarly journals of Journal of Autacoids & Hormones.

chronic skin disease

The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in MEDLINE, PUBMED, SCOPUS, COPERNICUS, CAS, EBSCO and ISI.Read More…..

The Effects of Non-interest Banking on Entrepreneurship in Nigeria

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Non-interest banking otherwise or also known as Islamic Banking is one which raised a lot of fumes in Nigeria and in the world over. Its usefulness as well as its religiosity raised a lot of controversy. Some have seen it as a good way of banking while others have given it a dismissal attitude.

Non-interest Banking

If this is so, we would like to know what this system of banking entails and whether it is useful to the society and to entrepreneurs. In doing so, it raises a question in our mind. That is, “What is Non- Interest Banking?”

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Non-interest banking or Islamic banking is banking or banking activity that is consistent with the principles of sharia and its practical application through the development of Islamic economics. Also, according to Charles M. Hudwick, in his book Banking Evolution, 2008, pg. 205, Islamic banking refers to a banking activity or a system of banking that is in consonance with the basic principles of Islamic Shraiah (Rules and values set by Islam).

The Increasing Relevance of FTIR Spectroscopy in Biomedicine

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Research into the utilization of FTIR based spectroscopic methods has been going on for close to about 25 years with the field expanding from the initial days of cancer diagnosis to now where it includes various diseases occurring due to pathogens, genetic and environmental factors as well as lifestyle and age related factors. In parallel there have been developments in terms of both instrumentation sophistication and computational methods, to make it more clinically appealing while increasing the sensitivity and specificity of the technique. As the field has diversified over the years, a few reports are highlighted that establish the growing acceptance of FTIR spectroscopy as a reliable technique in both basic and applied research in the field of biomedicine.

FTIR Spectroscopy in Biomedicine

The field of IR based diagnosis emerged with the validations that carcinogenic and normal tissues from various organs could be differentiated based on their absorbance in the IR region (mostly mid-IR) that was related to the alteration in the chemical composition. The concept of unique fingerprinting was subsequently well established with studies from many different laboratories reporting that each cell or tissue type ranging from microbial cell to complex human tissues have characteristic absorbance spectrum. Making the system of diagnosis reagent free has been the ultimate challenge in using the technique in routine clinical set ups.

Contact and Joint Forces Modeling and Simulation of Crawler-formation Interactions

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Cable shovels are used in surface mining operations to achieve economic bulk production capacities. The service life of the  rawlers and their shoes define shovel reliability, maintainability, availability and efficiency. The crawler track-terrain  interaction generates high time-fluctuating contact forces that result in stress buildup, crack and fatigue failure of    wler shoes. In addition, the link pins that connect two crawler shoes can exert large fluctuating pin loads on shoe lugding to shoe breakage. This paper addresses fundamental research into contact forces acting on crawler shoes, joint forces generated in the link pin and total deformation of the formation during shovel propel.

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Cable shovels are widely used in surface mining operations. The lower works of this shovel comprise propel and crawler systems, which support the upper body and attachment as shown in Figure 1.The crawler tracks are made up of crawler shoes that are connected together by link pins to form a continuous chain. The multi-body dynamics study on the interaction between the shovel crawler track and the terrain for large shovels in surface mining operations is not widely available in the open literature. This study is important to determine crawler shoe kinematics, contact forces between crawler tracks and ground and reaction forces at the link pin joint between adjacent crawler shoes

Psychosocial Impact and Quality of Life among Adult Egyptian Patients with Psoriasis

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This study was conducted on 100 adult patients with psoriasis, attending Dermatology Clinic, Al-Hussein University Hospital and an equal number of normal adults as controls. An analytic, case-control, clinic based study design was selected to conduct this research. An interviewing form and Middle Sex Hospital Questionnaire were used to survey psychosocial impact of the disease and psychiatric symptoms. Dermatology life quality index was used to assess disease impact on the patients’ QOL.

12.Psychosocial Impact

The most common statistically significant impact was the interference with daily activities (59.0%). This was higher in patients with severe disease (96.2%) and with disease affected visible areas of the body (70.6%). The depression was the commonest psychiatric symptom (27.0%); 46.2% and 35.3% in patients with severe disease and with disease affected visible areas of the body, respectively. QOL was poor in 73.0% of the patients; the most common affected QOL mean domains scores were symptoms and feelings (15.8 ± 5.4), personal relationships (14.6 ± 5.2), and daily activities (14.4 ± 4.9). All QOL mean domain scores were statistically significantly higher in patients with disease affected visible areas of the body and with severe disease.

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